Parathyroid hormone as a marker for metabolic bone disease of prematurity

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Calcitriol treatment in metabolic bone disease of prematurity with elevated parathyroid hormone: A preliminary study

Objective To describe the association of calcitriol treatment with the change in parathyroid hormone (PTH) and biochemical markers of bone disease in infants with metabolic bone disease of prematurity (MBD) and secondary hyperparathyroidism. Study design This retrospective chart review examined serum intact PTH, serum calcium (Ca), serum phosphorus (P), serum alkaline phosphatase (APA), urine...

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Metabolic bone disease of prematurity☆

Metabolic bone disease (MBD) of prematurity remains a significant problem for preterm, chronically ill neonates. The definition and recommendations for screening and treatment of MBD vary in the literature. A recent American Academy of Pediatrics Consensus Statement may help close the gap in institutional variation, but evidence based practice guidelines remain obscure due to lack of normative ...

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Osteopenia of prematurity has become a common problem recently because of improved survival rates of infants with very low birth weight (VLBW). The incidence of neonatal osteopenia is inversely correlated with gestational age and birth weight. Herein, we present four cases of preterm osteopenia that were referred to the pediatric endocrinology outpatient clinic with diverse clinical and laborat...

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Parathyroid hormone: critical bridge between bone metabolism and cardiovascular disease.

arathyroid hormone (PTH) is a principal regulator of calcium balance in physiological and pathological conditions associated with cardiovascular disorders and plays a major physiological role in bone homeostasis (Figure 1). PTH systemically controls bone remodeling by modulating the bone marrow microenvironment and regulating osteogenic signaling pathways. 1 PTH and its related peptide can have...

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ژورنال

عنوان ژورنال: Journal of Perinatology

سال: 2014

ISSN: 0743-8346,1476-5543

DOI: 10.1038/jp.2014.97